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Article

Noisy clues to the origin of life.

Proceedings. Biological sciences - 7 Dec 2002

Krakauer David C, Sasaki Akira

Abstract excerpt

The origin of stable self-replicating molecules represents a fundamental obstacle to the origin of life. The low fidelity of primordial replicators places restrictions on the quantity of information encoded in a primitive nucleic acid alphabet. Further difficulties for the origin of life are the role of drift in small primordial populations, reducing the rate of fixation of superior replicators, and the hostile...

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Identifiers

PMID: 12495484
DOI: 10.1098/rspb.2002.2127
PMCID: PMC1691173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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