Article
Use of site-directed mutagenesis to identify an upstream regulatory sequence of sodA gene of Escherichia coli K-12.
Proceedings of the National Academy of Sciences of the United States of America - 1 Apr 1990
Naik S M, Hassan H M
Abstract excerpt
Mn-containing superoxide dismutase (SodA; superoxide:superoxide oxidoreductase, EC 1.15.1.1) biosynthesis in Escherichia coli is regulated by several environmental stimuli. The DNA sequence of sodA shows the presence of a potential binding site for a regulatory protein(s) at the -35 region. To explore the possible role of this region in the regulation of sodA, we used oligonucleotide-directed site-specific...
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