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Article

The early history of tumor virology: Rous, RIF, and RAV.

Proceedings of the National Academy of Sciences of the United States of America - 30 Aug 2011

Rubin Harry

Abstract excerpt

One hundred years ago Peyton Rous recovered a virus, now known as the Rous sarcoma virus (RSV), from a chicken sarcoma, which reproduced all aspects of the tumor on injection into closely related chickens. There followed recovery of causal viruses of tumors of different morphology from 4 more of 60 chicken tumors. Subsequent studies in chickens of the biology of the first RSV isolated moved slowly for 45 y until...

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Identifiers

PMID: 21813762
DOI: 10.1073/pnas.1108655108
PMCID: PMC3167550

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