Article
Tagging SNPs in REN, AGTR1 and AGTR2 genes and response of renin activity, angiotensin II and aldosterone concentrations to antihypertensive treatment in Kazakans.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Dec 2011
Yan Weili, Zhang Yuanming, Shan Zimei, Wang Qian, Huang Yongdi, Wang Chenchen, Yan Kai
Abstract excerpt
HYPOTHESIS: Polymorphisms of REN, AGTR1 and AGTR2 may be associated with responses of renin-angiotensin-aldosterone system (RAAS) activity phenotypes to angiotensin-converting enzyme inhibitor (ACEI) antihypertensive treatment. MATERIALS AND METHODS: A total of 400 first diagnosed Kazak hypertensives were randomly allocated to two groups and received a 3-week course of either captopril and atenolol as monotherapy...
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