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Article

O2-dependent methionine auxotrophy in Cu,Zn superoxide dismutase-deficient mutants of Saccharomyces cerevisiae.

Journal of bacteriology - 1 Apr 1990

Chang E C, Kosman D J

Abstract excerpt

Mutant strains of the yeast Saccharomyces cerevisiae which lack functional Cu,Zn superoxide dismutase (SOD-1) do not grow aerobically unless supplemented with methionine. The molecular basis of this O2-dependent auxotrophy in one of the mutants, Dscd1-1C, has been investigated. Sulfate supported anaerobic but not aerobic mutant growth. On the other hand, cysteine and homocysteine supported aerobic growth while...

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Identifiers

PMID: 2180907
DOI: 10.1128/jb.172.4.1840-1845.1990
PMCID: PMC208677

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