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Article

O2-dependent methionine auxotrophy in Cu,Zn superoxide dismutase-deficient mutants of Saccharomyces cerevisiae.

Journal of bacteriology - 1 Apr 1990

Chang E C, Kosman D J

Abstract excerpt

Mutant strains of the yeast Saccharomyces cerevisiae which lack functional Cu,Zn superoxide dismutase (SOD-1) do not grow aerobically unless supplemented with methionine. The molecular basis of this O2-dependent auxotrophy in one of the mutants, Dscd1-1C, has been investigated. Sulfate supported anaerobic but not aerobic mutant growth. On the other hand, cysteine and homocysteine supported aerobic growth while...

Topics

Aerobiosis
Anaerobiosis
Cytosol
Methionine
Models, Biological
Mutation
Oxidoreductases Acting on Sulfur Group Donors
Oxygen Consumption
Saccharomyces cerevisiae
Sulfates
Sulfites

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sulfur Oxides

Superoxide Dismutase

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Identifiers

PMID: 2180907
DOI: 10.1128/jb.172.4.1840-1845.1990
PMCID: PMC208677

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2180907-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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