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Article

Ets family members induce lymphangiogenesis through physical and functional interaction with Prox1.

Journal of cell science - 15 Aug 2011

Yoshimatsu Yasuhiro, Yamazaki Tomoko, Mihira Hajime, Itoh Taichi, Suehiro Junichi, Yuki Keiko, Harada Kaori, Morikawa Masato, Iwata Caname, Minami Takashi, Morishita Yasuyuki, Kodama Tatsuhiko, Miyazono Kohei, Watabe Tetsuro

Abstract excerpt

Prox1 plays pivotal roles during embryonic lymphatic development and maintenance of adult lymphatic systems by modulating the expression of various lymphatic endothelial cell (LEC) markers, such as vascular endothelial growth factor receptor 3 (VEGFR3). However, the molecular mechanisms by which Prox1 transactivates its target genes remain largely unknown. Here, we identified Ets-2 as a candidate molecule that...

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Identifiers

PMID: 21807940
DOI: 10.1242/jcs.083998

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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