Article
Mutations that affect transcription and cyclic AMP-CRP regulation of the adenylate cyclase gene (cya) of Salmonella typhimurium.
Genetics - 1 Aug 1990
Fandl J P, Thorner L K, Artz S W
Abstract excerpt
We studied the expression of the cya promoter(s) in cya-lac fusion strains of Salmonella typhimurium and demonstrated cAMP receptor protein (CRP)-dependent repression by cAMP. Expression of cya was reduced about fourfold in cultures grown in acetate minimal medium as compared to cultures grown in...
Topics
- Acetates
- Adenylyl Cyclases
- Alleles
- Base Sequence
- Binding Sites
- Cloning, Molecular
- Culture Media
- Cyclic AMP
- Gene Expression Regulation, Bacterial
- Glucosephosphates
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Receptors, Cyclic AMP
- Salmonella typhimurium
- Transcription, Genetic