Article
The structural and functional diversity of dystrophin.
Nature genetics - 1 Apr 1993
Ahn A H, Kunkel L M
Abstract excerpt
Duchenne and Becker muscular dystrophies are caused by defects of the dystrophin gene. Expression of this large X-linked gene is under elaborate transcriptional and splicing control. At least five independent promoters specify the transcription of their respective alternative first exons in a cel...
Topics
- Alternative Splicing
- Animals
- Brain
- Cognition Disorders
- Dystrophin
- Exons
- Gene Expression
- Genetic Variation
- Mice
- Muscles
- Muscular Dystrophies
- Peripheral Nerves
- Promoter Regions, Genetic
- Transcription, Genetic
- X Chromosome