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DNA double-strand breaks induced by mammographic screening procedures in human mammary epithelial cells

29 Jul 2011

Abstract excerpt

PURPOSE: To assess in vitro mammographic radiation-induced DNA damage in mammary epithelial cells from 30 patients with low (LR) or high (HR) family risk of breast cancer. MATERIALS AND METHODS: Spontaneous and radiation-induced DNA double-strand breaks (DSB) were quantified by using immunofluorescence of the phosphorylated H2AX histone (γH2AX) in different conditions of mammography irradiation (2, 4, 2 + 2 mGy)....

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PMID: 21797809
DOI: 10.3109/09553002.2011.608410

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