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Critical Roles of microRNAs in the Pathogenesis of Fatty Liver: New Advances, Challenges, and Potential Directions.

Biochemical genetics - 1 Oct 2018

Miao Chenggui, Xie Zhongwen, Chang Jun

Abstract excerpt

In this review, we summarize the current understanding of microRNA (miRNA)-mediated modulation of the gene expression in the fatty liver as well as related signaling pathways. Because of the breadth and diversity of miRNAs, miRNAs may have a very wide variety of biological functions, and much evidence has confirmed that miRNAs are involved in the pathogenesis of fatty liver. In the pathophysiological mechanism of...

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Disease Models, Animal
Fatty Liver
Gene Expression Regulation
Gene Regulatory Networks
Genetic Markers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Therapy

Lipid Metabolism

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PMID: 29951838
DOI: 10.1007/s10528-018-9870-9

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