Article
CHEK2, MGMT, SULT1E1 and SULT1A1 polymorphisms and endometrial cancer risk.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Aug 2011
O'Mara Tracy A, Ferguson Kaltin, Fahey Paul, Marquart Louise, Yang Hannah P, Lissowska Jolanta, Chanock Stephen, Garcia-Closas Montserrat, Thompson Deborah J, Healey Catherine S, Dunning Alison M, Easton Douglas F, Webb Penelope M, Spurdle Amanda B
Abstract excerpt
Several single nucleotide polymorphisms (SNPs) in candidate genes of DNA repair and hormone pathways have been reported to be associated with endometrial cancer risk. We sought to confirm these associations in two endometrial cancer case-control sample sets and used additional data from an existing genome-wide association study to prioritize an additional SNP for further study. Five SNPs from the CHEK2, MGMT,...
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