Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Systemic upregulation of neutrophil α-defensins and serine proteases in neutrophilic asthma.

Thorax - 1 Nov 2011

Baines Katherine J, Simpson Jodie L, Wood Lisa G, Scott Rodney J, Gibson Peter G

Abstract excerpt

BACKGROUND: The well-characterised airway inflammatory phenotypes of asthma include eosinophilic, neutrophilic, mixed eosinophilic/neutrophilic and paucigranulocytic asthma, identified based on the proportion of sputum granulocytes. Systemic inflammation is now recognised as an important part of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Defensins
Share to Asthma
Share to Leukocyte Count

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neutrophils

Share to Real-Time Polymerase Chain Reaction

Share to Serine Proteases

Share to Sputum

Share to Up-Regulation

Source

Identifiers

PMID: 21785157
DOI: 10.1136/thx.2010.157719

Genes

CTSG
DEFA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21785157-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Systemic upregulation of neutrophil α-defensins and serine proteases in neutrophilic asthma.PMID 21785157Read ↗

The neutrophilic inflammatory phenotype is associated with systemic inflammation in asthma.Semantic proximity Read ↗

Transcriptomics of biopsies identifies novel genes and pathways linked to neutrophilic inflammation in severe asthmaSemantic proximity Read ↗

Modern View of Neutrophilic Asthma Molecular Mechanisms and Therapy.Semantic proximity Read ↗

Asthma inflammatory phenotypes on four continents: most asthma is non-eosinophilic.Semantic proximity Read ↗

Cellular mechanisms underlying eosinophilic and neutrophilic airway inflammation in asthma.Semantic proximity Read ↗

Neutrophilic Inflammation in Asthma and Association with Disease Severity.Semantic proximity Read ↗

Inflammatory phenotypes in stable and acute childhood asthma.Semantic proximity Read ↗

Detailed analysis of sputum and systemic inflammation in asthma phenotypes: are paucigranulocytic asthmatics really non-inflammatory?Semantic proximity Read ↗

Neutrophil phenotypes in bronchial airways differentiate single from dual responding allergic asthmatics.Semantic proximity Read ↗

Six gene and TH2 signature expression in endobronchial biopsies of participants with asthma.Semantic proximity Read ↗

Alpha-1-antitrypsin is produced by human neutrophil granulocytes and their precursors and liberated during granule exocytosis.Semantic proximity Read ↗

Blood inflammatory phenotypes were associated with distinct clinical expressions of asthma in adults from a large population-based cohort.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.