Article
Acquisition of steady-state operant behavior in long-living Ames Dwarf mice.
Physiology & behavior - 24 Oct 2011
Derenne Adam, Brown-Borg Holly, Feltman Kathryn, Corbett Grant, Lackman Serena
Abstract excerpt
Ames dwarf mice have a Prop-1 mutation that has been identified with increased levels of IGF-I in the central nervous system, upregulation of neuroprotective systems, and increased lifespan. To elucidate the behavioral effects of the Prop-1 mutation, 8 Ames dwarf and 7 normal mice (all of whom were 8 months of age or younger) were compared on a differential-reinforcement-of-low-rate-of-responding schedule of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.