Article
Of woods and webs: possible alternatives to the tree of life for studying genomic fluidity in E. coli.
Biology direct - 20 Jul 2011
Beauregard-Racine Julie, Bicep Cédric, Schliep Klaus, Lopez Philippe, Lapointe François-Joseph, Bapteste Eric
Abstract excerpt
BACKGROUND: We introduce several forest-based and network-based methods for exploring microbial evolution, and apply them to the study of thousands of genes from 30 strains of E. coli. This case study illustrates how additional analyses could offer fast heuristic alternatives to standard tree of life (TOL) approaches. RESULTS: We use gene networks to identify genes with atypical modes of evolution, and genome...
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