Article
Influence of genetic obesity, dietary carbohydrate and age on parameters of glucose tolerance and kidney and adrenal gland histology in female SHR/N-corpulent rats.
International journal of obesity - 1 Nov 1990
Michaelis O E, Carswell N, Velasquez M T, Kimmel P L, Abraham A A, Canary J J, Hansen C T
Abstract excerpt
Young female obese (cp/cp) and lean littermates (?/+) of the recently developed congenic strain, SHR/NIH-corpulent (SHR/N-cp), were fed for 6.5 months isocaloric diets containing 54 percent carbohydrate as either sucrose or starch. Glycemic, lipidemic and renal parameters were determined after 1, 3 and 6 months. Systolic blood pressure and plasma corticosterone levels were determined after 3 months. After 6.5...
Topics
- Adrenal Cortex
- Animals
- Blood Glucose
- Corticosterone
- Dietary Carbohydrates
- Female
- Glomerular Mesangium
- Glucose Tolerance Test
- Inclusion Bodies
- Insulin