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Article

Association of VKORC1 -1639 G>A polymorphism with carotid intima-media thickness in type 2 diabetes mellitus.

Diabetes research and clinical practice - 1 Nov 2011

Tavridou Anna, Petridis Ioannis, Vasileiadis Michail, Ragia Georgia, Heliopoulos Ioannis, Vargemezis Vassileios, Manolopoulos Vangelis G

Abstract excerpt

AIMS: Media calcification is a predictor of cardiovascular mortality in type 2 diabetes mellitus (T2DM). Undercarboxylation of some vitamin K-dependent proteins, due to genetic polymorphisms of VKORC1, can lead to calcification. We examined a potential association between VKORC1 -1639 G>A polymorphism and T2DM and, also, the association of this polymorphism with carotid intima-media thickness (cIMT). METHODS:...

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Source

Identifiers

PMID: 21767890
DOI: 10.1016/j.diabres.2011.06.021

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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