Article
Do all hemochromatosis patients have the same origin? An analysis of mitochondrial DNA and Y-DNA.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie - 1 Jun 2011
Symonette Caitlin J, Adams Paul C
Abstract excerpt
BACKGROUND: Mitochondrial DNA (mtDNA) and Y-DNA analysis have been widely used to predict ancestral origin. Genetic anthropologists predict that human civilizations may have originated in central Africa one to two million years previously. Primary iron overload is not a common diagnosis among indigenous people of northern Africa, but hereditary hemochromatosis is present in approximately one in 200 people in...
Topics
- Africa
- Canada
- Chromosomes, Human, Y
- DNA, Mitochondrial
- Emigration and Immigration
- Europe
- Genetic Predisposition to Disease
- Genetics, Population
- Genome-Wide Association Study
- Hemochromatosis