Article
Potential celiac patients: a model of celiac disease pathogenesis.
PloS one - 1 Jan 2011
Sperandeo Maria Pia, Tosco Antonella, Izzo Valentina, Tucci Francesca, Troncone Riccardo, Auricchio Renata, Romanos Jihane, Trynka Gosia, Auricchio Salvatore, Jabri Bana, Greco Luigi
Abstract excerpt
BACKGROUND AND AIM: Potential celiacs have the 'celiac type' HLA, positive anti-transglutaminase antibodies but no damage at small intestinal mucosa. Only a minority of them develops mucosal lesion. More than 40 genes were associated to Celiac Disease (CD) but we still do not know how those pathways transform a genetically predisposed individual into an affected person. The aim of the study is to explore the...
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