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Article

RFX6 is needed for the development and maintenance of the β-cell phenotype.

Islets - 1 Jan 2000

Taleb Nadine, Polychronakos Constantin

Abstract excerpt

RFX6 has recently been found to be essential for the development of the endocrine pancreas through studies in both humans and mice. Interestingly, this gene maintains a specific expression in the postnatal hormone producing cells of the pancreas. Moreover in humans, different types of diabetes mellitus affect obligate carriers of RFX6 mutations. Therefore, RFX6 appears to have a pivotal role in the maintenance of...

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Source

Identifiers

PMID: 21750414
DOI: 10.4161/isl.3.5.15944

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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