Article
Detection, semiquantitation, and genetic variation in hepatitis C virus sequences amplified from the plasma of blood donors with elevated alanine aminotransferase.
The Journal of clinical investigation - 1 Nov 1990
Ulrich P P, Romeo J M, Lane P K, Kelly I, Daniel L J, Vyas G N
Abstract excerpt
Hepatitis C virus (HCV) is the predominant etiologic agent of posttransfusion non-A, non-B hepatitis, characterized by undulating elevation of alanine aminotransferase (ALT) and chronic liver disease. A commercial enzyme-linked immunosorbent assay detected antibodies to HCV (anti-HCV) in 11 speci...
Topics
- Alanine Transaminase
- Animals
- Base Sequence
- DNA
- Genetic Variation
- Hepacivirus
- Hepatitis Antibodies
- Hepatitis B Antibodies
- Hepatitis B Surface Antigens
- Humans
- Molecular Sequence Data
- Polymerase Chain Reaction
- RNA, Viral