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ABCC1 polymorphism Arg723Gln (2168G> A) is associated with lung cancer susceptibility in a Chinese population.

Clinical and experimental pharmacology & physiology - 1 Sept 2011

Yin Ji-Ye, Han Li-Fang, Huang Qiong, Xu Xiao-Jing, Zhou Hong-Hao, Liu Zhao-Qian

Abstract excerpt

1. In a previous in vitro study, we showed that the Arg723Gln (2168G > A) polymorphism significantly ABCC1-induced multidrug resistance. The aim of the present study was to further investigate the association of this polymorphism with lung cancer susceptibility and chemotherapy response in a Chinese population. 2. A total of 77 lung cancer patients (54 men, 23 women) and 71 cancer-free controls (49 men, 22 women)...

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Identifiers

PMID: 21736601
DOI: 10.1111/j.1440-1681.2011.05571.x

Genes

ABCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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