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Article

Pleural mesothelioma side populations have a precursor phenotype.

Carcinogenesis - 1 Sept 2011

Frei Claudia, Opitz Isabelle, Soltermann Alex, Fischer Bruno, Moura Ubiratan, Rehrauer Hubert, Weder Walter, Stahel Rolf, Felley-Bosco Emanuela

Abstract excerpt

DyeCycleViolet was used to set up the side population (SP) functional assay aimed at identifying subpopulations of malignant pleural mesothelioma (MPM) tumor cells with chemoresistance phenotype associated with ABCG2 transporter activity. Self-renewal, chemoresistance and tumorigenicity were tested for SP and non-side population (NSP) cells. Tumors were characterized by mesothelin, calretinin, N-cadherin, D2-40...

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Source

Identifiers

PMID: 21729925
DOI: 10.1093/carcin/bgr127

Genes

ABCG2

Provenance

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