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Exome-wide DNA capture and next generation sequencing in domestic and wild species.

BMC genomics - 5 Jul 2011

Cosart Ted, Beja-Pereira Albano, Chen Shanyuan, Ng Sarah B, Shendure Jay, Luikart Gordon

Abstract excerpt

BACKGROUND: Gene-targeted and genome-wide markers are crucial to advance evolutionary biology, agriculture, and biodiversity conservation by improving our understanding of genetic processes underlying adaptation and speciation. Unfortunately, for eukaryotic species with large genomes it remains costly to obtain genome sequences and to develop genome resources such as genome-wide SNPs. A method is needed to allow...

Topics

Animals
Cattle
Exons
Female
Genome
Genotype
Polymorphism, Single Nucleotide
Sequence Analysis, DNA
Software
X Chromosome

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21729323
DOI: 10.1186/1471-2164-12-347
PMCID: PMC3146453

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