Article
Increased prevalence of impaired fasting glucose in MEN1 gene mutation carriers.
Clinical endocrinology - 1 Jan 2012
van Wijk J P H, Dreijerink K M A, Pieterman C R C, Lips C J M, Zelissen P M J, Valk G D
Abstract excerpt
OBJECTIVE: Multiple endocrine neoplasia type 1 (MEN1) is a hereditary syndrome characterized by parathyroid, gastroenteropancreatic, pituitary and adrenal tumours. Cardiovascular disease has been identified as an important cause of death in MEN1 patients. Menin, the product of the MEN1 gene, is a co-activator for peroxisome proliferator-activated receptor-γ and the vitamin D receptor, which are involved in...
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