Article
MEN1 gene mutations in Hungarian patients with multiple endocrine neoplasia type 1.
Clinical endocrinology - 1 Nov 2007
Balogh Katalin, Hunyady Laszlo, Patocs Attila, Gergics Peter, Valkusz Zsuzsa, Toth Miklos, Racz Karoly
Abstract excerpt
OBJECTIVE: Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant hereditary disorder associated with mutations of the MEN1 gene. MEN1 may present as a familial or a sporadic disorder, with multiple endocrine tumours including parathyroid adenomas or hyperplasias, and pancreatic endocrine and pituitary gland tumours. The aim of this study was to examine the prevalence and spectrum of MEN1 gene...
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