Article
Genetic polymorphism of low-density lipoprotein receptor did not affect treatment outcome of chronic hepatitis C genotype 3.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet - 1 Feb 2011
Tanwandee Tawesak, Pithukpakorn Manop, Vipatakul Noppawan, Charatcharoenwitthaya Phunchai, Chainuvati Siwaporn, Nimanong Supot, Prachayakul Varayu, Pongprasobchai Supot, Manatsathit Sathaporn, Leelakusolvong Somchai, Pausawasdi Nonthalee, Kachintorn Udom, Limwongse Chanin, Udompunturak Suthipol
Abstract excerpt
BACKGROUND: The low-density lipoprotein receptor (LDL-R) has been proposed to function as a receptor for the hepatitis C virus (HCV) entry. Polymorphism of LDL-R gene may influence the clearance of virus and response to treatment. This study was conducted to evaluate the association of LDL-R gene polymorphism and the response to antiviral treatment in patients with chronic HCV infection. MATERIAL AND METHOD: A...
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