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Article

Induced pluripotent stem cell models from X-linked adrenoleukodystrophy patients.

Annals of neurology - 1 Sept 2011

Jang Jiho, Kang Hoon-Chul, Kim Han-Soo, Kim Ji Young, Huh Yong Jun, Kim Dae-Sung, Yoo Jeong-Eun, Lee Jeong-Ah, Lim Boyoung, Lee Jiwon, Yoon Tae-Min, Park In-Hyun, Hwang Dong-Youn, Daley George Q, Kim Dong-Wook

Abstract excerpt

OBJECTIVE: Because of a lack of an appropriate animal model system and the inaccessibility of human oligodendrocytes in vivo, X-linked adrenoleukodystrophy (X-ALD)-induced pluripotent stem cells (iPSCs) would provide a unique cellular model for studying etiopathophysiology and development of therapeutics for X-ALD. METHODS: We generated and characterized iPSCs of the 2 major types of X-ALD, childhood cerebral ALD...

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Source

Identifiers

PMID: 21721033
DOI: 10.1002/ana.22486

Genes

AMN
ABCD1
ABCD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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