Article
ATP13A2 variability in Taiwanese Parkinson's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Sept 2011
Chen Chiung-Mei, Lin Chih-Hsin, Juan Hsueh-Fen, Hu Fen-Ju, Hsiao Ya-Chin, Chang Hsin-Yi, Chao Chih-Ying, Chen I-Cheng, Lee Li-Ching, Wang Tsu-Wei, Chen Ya-Tang, Chen Yi-Tsun, Lee-Chen Guey-Jen, Wu Yih-Ru
Abstract excerpt
Mutations in ATP13A2 have been reported to associate with Parkinson's disease (PD). This study investigates the contribution of genetic variants in ATP13A2 to Taiwanese PD. ATP13A2 cDNA fragments from 65 early onset PD (onset <50 years) were sequenced. The identified variants were validated in a cohort of PD (n = 493) and ethnically matched controls (n = 585). A novel heterozygous G1014S, located at the conserved...
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