Article
Genetic diversity and population structure of the endangered marsupial Sarcophilus harrisii (Tasmanian devil).
Proceedings of the National Academy of Sciences of the United States of America - 26 Jul 2011
Miller Webb, Hayes Vanessa M, Ratan Aakrosh, Petersen Desiree C, Wittekindt Nicola E, Miller Jason, Walenz Brian, Knight James, Qi Ji, Zhao Fangqing, Wang Qingyu, Bedoya-Reina Oscar C, Katiyar Neerja, Tomsho Lynn P, Kasson Lindsay McClellan, Hardie Rae-Anne, Woodbridge Paula, Tindall Elizabeth A, Bertelsen Mads Frost, Dixon Dale, Pyecroft Stephen, Helgen Kristofer M, Lesk Arthur M, Pringle Thomas H, Patterson Nick, Zhang Yu, Kreiss Alexandre, Woods Gregory M, Jones Menna E, Schuster Stephan C
Abstract excerpt
The Tasmanian devil (Sarcophilus harrisii) is threatened with extinction because of a contagious cancer known as Devil Facial Tumor Disease. The inability to mount an immune response and to reject these tumors might be caused by a lack of genetic diversity within a dwindling population. Here we report a whole-genome analysis of two animals originating from extreme northwest and southeast Tasmania, the maximal...
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