Article
A novel triple mix radiobinding assay for the three ZnT8 (ZnT8-RWQ) autoantibody variants in children with newly diagnosed diabetes.
Journal of immunological methods - 31 Aug 2011
Vaziri-Sani Fariba, Delli Ahmed J, Elding-Larsson Helena, Lindblad Bengt, Carlsson Annelie, Forsander Gun, Ivarsson Sten A, Ludvigsson Johnny, Marcus Claude, Lernmark Åke
Abstract excerpt
BACKGROUND AND AIMS: Autoantibodies against the zinc transporter 8 (ZnT8A) are common in type 1 diabetes (T1D). ZnT8A analyses are complicated by the fact that there are three variants of the autoantigen at amino acid position 325 representing ZnT8-R (Arginine), ZnT8-W (Tryptophan) and ZnT8-Q (Gl...
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