Article
The dioxygenase-encoding olsD gene from Burkholderia cenocepacia causes the hydroxylation of the amide-linked fatty acyl moiety of ornithine-containing membrane lipids.
Biochemistry - 26 Jul 2011
González-Silva Napoleón, López-Lara Isabel M, Reyes-Lamothe Rodrigo, Taylor Adrian M, Sumpton David, Thomas-Oates Jane, Geiger Otto
Abstract excerpt
Burkholderia cenocepacia is an important opportunistic pathogen, and one of the most striking features of the Burkholderia genus is the collection of polar lipids present in its membrane, including phosphatidylethanolamine (PE) and ornithine-containing lipids (OLs), as well as the 2-hydroxylated derivatives of PE and OLs (2-OH-PE and 2-OH-OLs, respectively), which differ from the standard versions by virtue of...
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