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Article

OCT2, SSX and SAGE1 reveal the phenotypic heterogeneity of spermatocytic seminoma reflecting distinct subpopulations of spermatogonia.

The Journal of pathology - 1 Aug 2011

Lim Jasmine, Goriely Anne, Turner Gareth Dh, Ewen Katherine A, Jacobsen Grete Krag, Graem Niels, Wilkie Andrew Om, Rajpert-De Meyts Ewa

Abstract excerpt

Spermatocytic seminoma (SS) is a rare testicular neoplasm that occurs predominantly in older men. In this study, we aimed to shed light on the histogenesis of SS by investigating the developmental expression of protein markers that identify distinct subpopulations of human spermatogonia in the normal adult testis. We analysed the expression pattern of OCT2, SSX2-4, and SAGE1 in 36 SS cases and four intratubular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Fibroblast Growth Factor, Type 3

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Source

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Identifiers

PMID: 21706474
DOI: 10.1002/path.2919
PMCID: PMC3210831

Genes

SSX2
SAGE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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