Article
Fluorescence in situ hybridization and K-ras analyses improve diagnostic yield of endoscopic ultrasound-guided fine-needle aspiration of solid pancreatic masses.
Pancreas - 1 Oct 2011
Reicher Sofiya, Boyar Fatih Z, Albitar Maher, Sulcova Vladimira, Agersborg Sally, Nga Visal, Zhou Ying, Li Gang, Venegas Rose, French Samuel W, Chung David S, Stabile Bruce E, Eysselein Viktor E, Anguiano Arturo
Abstract excerpt
OBJECTIVES: Endoscopic ultrasound (EUS)-guided fine-needle aspiration (FNA) is the main diagnostic modality for pancreatic mass lesions. However, cytology is often indeterminate, leading to repeat FNAs and delay in care. Here, we evaluate whether combining routine cytology with fluorescence in situ hybridization (FISH) and K-ras/p53 analyses improves diagnostic yield of pancreatic EUS-FNA. METHODS: Fifty EUS-FNAs...
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