Article
Antibiotic exposure and resistance development in Pseudomonas aeruginosa and Enterobacter species in intensive care units.
Critical care medicine - 1 Nov 2011
Ong David S Y, Jongerden Irene P, Buiting Anton G, Leverstein-van Hall Maurine A, Speelberg Ben, Kesecioglu Jozef, Bonten Marc J M
Abstract excerpt
OBJECTIVES: We quantified the association between antibiotic exposure and acquisition of antibiotic resistance in Pseudomonas aeruginosa and Enterobacter species in intensive care unit patients. DESIGN: Prospective cohort study. SETTING AND PATIENTS: In 1,201 patients, respiratory tract colonization was determined through regular screening on admission, twice weekly, and on discharge. Primary outcome was the...
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