Carbapenem resistance dynamics in clinical Pseudomonas aeruginosa isolates from a tertiary hospital in Valparaíso, Chile, 2019-2024.

doi:10.1016/j.jgar.2026.06.026

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Article

Carbapenem resistance dynamics in clinical Pseudomonas aeruginosa isolates from a tertiary hospital in Valparaíso, Chile, 2019-2024.

Journal of global antimicrobial resistance - 1 Sept 2026

Vera-Rojo Germán, Cerda-Solar Paula, Gamboa-Vallejos Estefanía, Poblete-Roa María M, Lira-Velásquez Diego, Vásquez-Ponce Felipe, Muñoz-Rocha Rubén, Olivares-Pacheco Jorge

Abstract excerpt

BACKGROUND: Pseudomonas aeruginosa is a major cause of healthcare-associated infections and a World Health Organization priority pathogen because of its marked ability to develop resistance to last-line antibiotics. Carbapenem resistance may arise through chromosomal mutations, acquisition of resistance genes, and clonal dissemination under sustained antimicrobial pressure. OBJECTIVE: To investigate the temporal...

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Topics

Pseudomonas aeruginosa
Humans
Carbapenems
Tertiary Care Centers
Chile

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Pseudomonas Infections

Anti-Bacterial Agents

Microbial Sensitivity Tests

beta-Lactamases

Bacterial Proteins

Whole Genome Sequencing

Mutation

Porins

Membrane Transport Proteins

Drug Resistance, Multiple, Bacterial

Bacterial Outer Membrane Proteins

Source

Open in PubMed

Identifiers

PMID: 42419644
DOI: 10.1016/j.jgar.2026.06.026

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