Article
The Fsr quorum-sensing system of Enterococcus faecalis modulates surface display of the collagen-binding MSCRAMM Ace through regulation of gelE.
Journal of bacteriology - 1 Sept 2011
Pinkston Kenneth L, Gao Peng, Diaz-Garcia Daniel, Sillanpää Jouko, Nallapareddy Sreedhar R, Murray Barbara E, Harvey Barrett R
Abstract excerpt
Ace, a known virulence factor and the first identified microbial surface component recognizing adhesive matrix molecule (MSCRAMM) of Enterococcus faecalisis associated with host cell adherence and endocarditis. The Fsr quorum-sensing system of E. faecalis, a two-component signal transduction system, has also been repeatedly linked to virulence in E. faecalis, due in part to the transcriptional induction of an...
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