Article
Drosophila host model reveals new enterococcus faecalis quorum-sensing associated virulence factors.
PloS one - 1 Jan 2013
Teixeira Neuza, Varahan Sriram, Gorman Matthew J, Palmer Kelli L, Zaidman-Remy Anna, Yokohata Ryoji, Nakayama Jiro, Hancock Lynn E, Jacinto António, Gilmore Michael S, de Fátima Silva Lopes Maria
Abstract excerpt
Enterococcus faecalis V583 is a vancomycin-resistant clinical isolate which belongs to the hospital-adapted clade, CC2. This strain harbours several factors that have been associated with virulence, including the fsr quorum-sensing regulatory system that is known to control the expression of GelE and SprE proteases. To discriminate between genes directly regulated by Fsr, and those indirectly regulated as the...
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