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Self-recognition in social amoebae is mediated by allelic pairs of tiger genes.

Science (New York, N.Y.) - 22 Jul 2011

Hirose Shigenori, Benabentos Rocio, Ho Hsing-I, Kuspa Adam, Shaulsky Gad

Abstract excerpt

Free-living cells of the social amoebae Dictyostelium discoideum can aggregate and develop into multicellular fruiting bodies in which many die altruistically as they become stalk cells that support the surviving spores. Dictyostelium cells exhibit kin discrimination--a potential defense against cheaters, which sporulate without contributing to the stalk. Kin discrimination depends on strain relatedness, and the...

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Amino Acid Sequence
Cell Adhesion
Cell Aggregation
Dictyostelium
Gene Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Protozoan

Protein Binding

Protozoan Proteins

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Identifiers

PMID: 21700835
DOI: 10.1126/science.1203903
PMCID: PMC3142563

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Self-recognition in social amoebae is mediated by allelic pairs of tiger genes.PMID 21700835Read ↗

Cellular allorecognition and its roles in Dictyostelium development and social evolution.Semantic proximity Read ↗

The polymorphic proteins TgrB1 and TgrC1 function as a ligand-receptor pair in Dictyostelium allorecognition.Semantic proximity Read ↗

Allorecognition, via TgrB1 and TgrC1, mediates the transition from unicellularity to multicellularity in the social amoeba Dictyostelium discoideum.Semantic proximity Read ↗

Kin recognition protects cooperators against cheaters.Semantic proximity Read ↗

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Hypermutable hotspot enables the rapid evolution of self/non-self recognition genes in Dictyostelium.Semantic proximity Read ↗

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