Article
Identification of Campylobacter jejuni genes contributing to acid adaptation by transcriptional profiling and genome-wide mutagenesis.
Applied and environmental microbiology - 1 Mar 2008
Reid Anne N, Pandey Reenu, Palyada Kiran, Whitworth Lisa, Doukhanine Evgueni, Stintzi Alain
Abstract excerpt
In order to cause disease, the food- and waterborne pathogen Campylobacter jejuni must face the extreme acidity of the host stomach as well as cope with pH fluctuations in the intestine. In the present study, C. jejuni NCTC 11168 was grown under mildly acidic conditions mimicking those encountered in the intestine. The resulting transcriptional profiles revealed how this bacterium fine-tunes gene expression in...
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