Article
Expression of MET and SOX2 genes in non-small cell lung carcinoma with EGFR mutation.
Oncology reports - 1 Oct 2011
Cai Yi-Ran, Zhang Hai-Qing, Qu Yang, Mu Jing, Zhao Dan, Zhou Li-Juan, Yan Hong, Ye Jian-Wei, Liu Yan
Abstract excerpt
Non-small cell lung carcinoma (NSCLC) is a leading cause of cancer-related deaths. Aberrance of the two oncogenes MET and SOX2 are frequently encountered in NSCLC. Exons 18 through 21 of the EGFR gene were screened and MET and SOX2 immunostaining was conducted to analyze the immunohistological staining of MET and SOX2 and the EGFR mutation status. One hundred and fifty tissue samples were examined including 57...
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