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Article

Inhibition of Cell Proliferation by an Anti-EGFR Aptamer

8 Jun 2011

Abstract excerpt

Aptamers continue to receive interest as potential therapeutic agents for the treatment of diseases, including cancer. In order to determine whether aptamers might eventually prove to be as useful as other clinical biopolymers, such as antibodies, we selected aptamers against an important clinical target, human epidermal growth factor receptor (hEGFR). The initial selection yielded only a single clone that could...

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Share to Advanced biosensing and bioanalysis techniques
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PMID: 21687663
DOI: 10.1371/journal.pone.0020299

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