Article
Intermediate volume on computed tomography imaging defines a fibrotic compartment that predicts glomerular filtration rate decline in autosomal dominant polycystic kidney disease patients.
The American journal of pathology - 1 Aug 2011
Caroli Anna, Antiga Luca, Conti Sara, Sonzogni Aurelio, Fasolini Giorgio, Ondei Patrizia, Perico Norberto, Remuzzi Giuseppe, Remuzzi Andrea
Abstract excerpt
Total kidney and cyst volumes have been used to quantify disease progression in autosomal dominant polycystic kidney disease (ADPKD), but a causal relationship with progression to renal failure has not been demonstrated. Advanced image processing recently allowed to quantify extracystic tissue, and to identify an additional tissue component named "intermediate," appearing hypoenhanced on contrast-enhanced...
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