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Article

The value of genotypic and imaging information to predict functional and structural outcomes in ADPKD.

JCI insight - 6 Aug 2020

Lavu Sravanthi, Vaughan Lisa E, Senum Sarah R, Kline Timothy L, Chapman Arlene B, Perrone Ronald D, Mrug Michal, Braun William E, Steinman Theodore I, Rahbari-Oskoui Frederic F, Brosnahan Godela M, Bae Kyongtae T, Landsittel Douglas, Chebib Fouad T, Yu Alan Sl, Torres Vicente E, Harris Peter C

Abstract excerpt

BACKGROUNDA treatment option for autosomal dominant polycystic kidney disease (ADPKD) has highlighted the need to identify rapidly progressive patients. Kidney size/age and genotype have predictive power for renal outcomes, but their relative and additive value, plus associated trajectories of disease progression, are not well defined.METHODSThe value of genotypic and/or kidney imaging data (Mayo Imaging Class;...

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Topics

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Share to Disease Progression
Share to Glomerular Filtration Rate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Image Processing, Computer-Assisted

Share to Kidney

Share to Kidney Failure, Chronic

Share to Polycystic Kidney, Autosomal Dominant

Share to Tomography, X-Ray Computed

Share to TRPP Cation Channels

Source

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Identifiers

PMID: 32634120
DOI: 10.1172/jci.insight.138724
PMCID: PMC7455088

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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