Article
Volume progression in polycystic kidney disease.
The New England journal of medicine - 18 May 2006
Grantham Jared J, Torres Vicente E, Chapman Arlene B, Guay-Woodford Lisa M, Bae Kyongtae T, King Bernard F, Wetzel Louis H, Baumgarten Deborah A, Kenney Phillip J, Harris Peter C, Klahr Saulo, Bennett William M, Hirschman Gladys N, Meyers Catherine M, Zhang Xiaoling, Zhu Fang, Miller John P
Abstract excerpt
BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive enlargement of cyst-filled kidneys. METHODS: In a three-year study, we measured the rates of change in total kidney volume, total cyst volume, and iothalamate clearance in patients with ADPKD. Of a total of 241 patients, in 232 patients without azotemia who were 15 to 46 years old at baseline we used...
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