Article
Genome-wide genetic marker discovery and genotyping using next-generation sequencing.
Nature reviews. Genetics - 17 Jun 2011
Davey John W, Hohenlohe Paul A, Etter Paul D, Boone Jason Q, Catchen Julian M, Blaxter Mark L
Abstract excerpt
The advent of next-generation sequencing (NGS) has revolutionized genomic and transcriptomic approaches to biology. These new sequencing tools are also valuable for the discovery, validation and assessment of genetic markers in populations. Here we review and discuss best practices for several NGS methods for genome-wide genetic marker development and genotyping that use restriction enzyme digestion of target...
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