Article
Outcome of patients with acute myeloid leukemia with monosomal karyotype who undergo hematopoietic cell transplantation
17 Jun 2011
Abstract excerpt
Monosomal karyotype (MK), defined as ≥ 2 autosomal monosomies or a single monosomy in the presence of other structural abnormalities, was confirmed by several studies to convey an extremely poor prognosis in patients with acute myeloid leukemia (AML) with a 4-year overall survival after diagnosis of < 4%. A recent investigation by the Southwest Oncology Group found that the only MK(+) patients alive and disease...
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