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Monosomal karyotype in adult acute myeloid leukemia: prognostic impact and outcome after different treatment strategies

17 Nov 2011

Abstract excerpt

We aimed to determine the prognostic impact of monosomal karyotype (MK) in acute myeloid leukemia (AML) in the context of the current World Health Organization (WHO) classification and to evaluate the outcome of MK(+) patients after allogeneic HSCT. Of 1058 patients with abnormal cytogenetics, 319 (30%) were MK MK(+). MK(+) patients were significantly older (P = .0001), had lower white blood counts (P = .0006),...

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PMID: 22096250
DOI: 10.1182/blood-2011-07-367508

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