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Article

Polymorphisms in the P450 c17 (17-hydroxylase/17, 20-Lyase) gene: association with estradiol and testosterone concentration in hypospadias.

Urology - 1 Oct 2011

Yadav Chandra Shekhar, Bajpai Minu, Kumar Vivek, Datta Sudip Kumar, Gupta Piyush, Ahmed Rafat Sultana, Banerjee Basu Dev

Abstract excerpt

OBJECTIVE: To investigate the association of CYP17 polymorphism with 17β-estradiol (E2) and testosterone (T) concentration in hypospadias. METHODS: Two-hundred twenty-three boys (91 with hypospadias and 132 age-matched controls) were included in the study. CYP17 polymorphism was evaluated using the polymerase chain reaction-restriction fragment length polymorphism method, whereas T and E2 levels were estimated in...

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PMID: 21676446
DOI: 10.1016/j.urology.2011.04.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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