Article
Overexpression of a leaderless form of yeast cytochrome c oxidase subunit Va circumvents the requirement for a leader peptide in mitochondrial import.
Molecular and cellular biology - 1 Sept 1990
Dircks L K, Poyton R O
Abstract excerpt
Subunit Va of Saccharomyces cerevisiae cytochrome c oxidase is a nucleus-encoded mitochondrial protein that is derived from a precursor with a 20-residue leader peptide. We previously reported that this leader peptide is required for import of subunit Va into mitochondria in vivo (S. M. Glaser, C. E. Trueblood, L. K. Dircks, R. O. Poyton, and M. G. Cumsky, J. Cell. Biochem. 36:275-278, 1988). Here we show that...
Topics
- Cell Nucleus
- Electron Transport Complex IV
- Gene Expression
- Genes, Fungal
- Genotype
- Macromolecular Substances
- Mitochondria
- Mutation
- Plasmids
- Protein Sorting Signals
- Saccharomyces cerevisiae
