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MicroRNA in Osteoarthritis

1 Feb 2011

Abstract excerpt

Osteoarthritis (OA) is the most prevalent degenerative joint disease and is accompanied by pain and joint dysfunction. Its clinical treatment tends to be unsatisfactory. Novel targets in OA include genes that are involved in OA pathophysiology and have been discovered using gene network, epigenetic and microRNA (miRNA) approaches. miRNA has been implicated in important cellular processes such as lipid metabolism,...

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PMID: 21672302
DOI: 10.1177/147323001103900101

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